Protective effects of Hawthorn (Crataegus oxyacantha) extract against digoxin-induced arrhythmias in rats

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Protective effects of Hawthorn (Crataegus oxyacantha) extract against digoxin-induced arrhythmias in rats

OBJECTIVE Digitalis preparations are commonly used by children and adults with heart diseases worldwide, although excessive doses may cause cardiac effects. The aim of the study is to evaluate the antiarrhythmic effect of Crataegus oxyacantha extract on digoxin-induced arrhythmias in anesthetized Wistar rats. METHODS Control and experimental groups were evaluated for arrhythmias induced by di...

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Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha).

Hawthorn, an herbal supplement, is currently being evaluated for the treatment of heart failure. The flavonoid components of hawthorn may be responsible for hawthorn's beneficial effects in the treatment of heart failure. However, these components may also affect P-glycoprotein function and cause interactions with drugs that are P-glycoprotein substrates, such as digoxin, which is also used to ...

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Crataegus oxyacantha Linn . commonly known as Hawthorn - A Scientific Review

Nature has been a source of medicinal agents for thousands of years and an impressive number of modern drugs has been isolated from natural sources, many based on their use in traditional medicine.Plant extracts are attractive sources of new drugs and have been shown to produce promising results in the treatment of various diseases.Crataegus oxyacantha Linn., commonly known as Hawthorn, is one ...

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Crataegus monogyna fruit aqueous extract as a protective agent against doxorubicin-induced reproductive toxicity in male rats

Objective: Doxorubicin (DOX) is a broad spectrum chemotherapeutic agent used in the treatment of several malignancies. The use of DOX in clinical chemotherapy has been restricted due to its diverse toxicities, including reproductive toxicity. Crataegus monogyna (C. monogyna) is one of the oldest medicinal plants that have been shown to be cytoprotective because of scavenging free radicals. The ...

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ژورنال

عنوان ژورنال: The Anatolian Journal of Cardiology

سال: 2015

ISSN: 2149-2263,2149-2271

DOI: 10.5152/akd.2014.5869